View Konstantin Vodopyanov, 2008 CLEO Program Co-Chair, and Aephraim Steinberg, 2008 QELS Program Co-Chair, discussing nonlinear optics in biology.

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Nonlinear Optics in Biology

Below are select presentations on this topic. To find additional relevant papers and sessions, visit the online conference program.

CWK6 • Spatial Phase Shaping in Nonlinear Microscopy
Wednesday, May 7, 6:00 p.m.–6:30 p.m., Room J2
Eric Olaf Potma; Univ. of California at Irvine, USA. The contrast in nonlinear coherent microscopy is improved by using spatial phase shaping of the incident laser beams. This approach exhibits promising applications for biomedical imaging studies.

CMS4 • In vivo Cellular Level Imaging Using Nonlinear Optical Microendoscopy
Monday, May 5, 2:15 p.m.–2:45 p.m., Ballroom A3 and A6
Mark Schnitzer; Stanford Univ., USA. Multiple contrast modalities can be used to perform minimally invasive optical microendoscopy in live subjects. I will describe applications of second-harmonic generation and one- and two-photon excited fluorescence microendoscopy in the mammalian nervous system.

Joint CLEO/QELS Symposium on Nonlinear Microscopy and Spectroscopy in Biology
Nonlinear optical techniques have equipped researchers with new tools for examining biological samples. The use of ultrafast pulses in multi-dimensional spectroscopy and coherent Raman spectroscopy have provided a closer look at the ultrafast dynamics and structure/function relationships of biological compounds. In combination with tight focusing, ultrafast lasers have also generated new imaging contrast mechanisms, such as coherent anti-Stokes Raman scattering, two-phonon absorption, sum frequency generation, and stimulated emission depletion, for the study of microscopic architecture, dynamics and composition of biological systems. In this symposium, the fields of nonlinear spectroscopy and microscopy are combined to sketch a unifying picture of the significant impact of ultrafast technologies on biology.